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Publications: Publications

2024

  • Molitor A, Lederle A, Radosavljevic M, Sapuru V, Zavorka Thomas ME, Yang J, Shirin M, Collin-Bund V, Jerabkova-Roda K, Miao Z, Bernard A, Rolli V, Grenot P, Castro CN, Rosenzwajg M, Lewis EG, Person R, Esperón-Moldes US, Kaare M, Nokelainen PT, Batzir NA, Hoffer GZ, Paul N, Stemmelen T, Naegely L, Hanauer A, Bibi-Triki S, Grün S, Jung S, Busnelli I, Tripolszki K, Al-Ali R, Ordonez N, Bauer P, Song E, Zajo K, Partida-Sanchez S, Robledo-Avila F, Kumanovics A, Louzoun Y, Hirschler A, Pichot A, Toker O, Mejía CAM, Parvaneh N, Knapp E, Hersh JH, Kenney H, Delmonte OM, Notarangelo LD, Goetz JG, Kahwash SB, Carapito C, Bajwa RPS, Thomas C, Ehl S, Isidor B, Carapito R, Abraham RS, Hite RK, Marcus N, Bertoli-Avella A, Bahram S. A pleiotropic recurrent dominant ITPR3 variant causes a complex multisystemic disease. Science Advances. 2024; Sep 13;10(37):eado5545 https://www-science-org.proxy.insermbiblio.inist.fr/doi/10.1126/sciadv.ado5545
     

  • Brychka D, Ayala-Nunez NV, Dupas A, Bare Y, Partiot E, Mittelheisser V, Lucansky V, Goetz JG, Osmani N, Gaudin R . Targeting monocytic Occludin impairs transendothelial migration and HIV neuroinvasion. EMBO Reports 2024; Aug;25(8):3276-3299. https://www-embopress-org.proxy.insermbiblio.inist.fr/doi/full/10.1038/s44319-024-00190-x
     

  • Garcia-Leon MJ, Liboni C, Mittelheisser V, Bochler L, [...] Lefebvre O, Mangin PH, Goetz JG. Platelets favor the outgrowth of established metastases. Nature Communications 2024; 15(1):3297. https://www.nature.com/articles/s41467-024-47516-w.pdf

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2023

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  • Karreman MA, Bauer AT, [...], Goetz JG, Schwab Y, Wick W, Winkler F. Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization. Cancer Research. 2023. doi:10.1158/0008-5472.CAN-22-3964

2022

  • ​​Peralta M, Osmani N, Goetz JG. Circulating tumor cells: Towards mechanical phenotyping of metastasis. iScience. 2022. doi:10.1016/j.isci.2022.103969

 

  • Jerabkova-Roda K, Dupas A, Osmani N, Hyenne V, Goetz JG. Circulating extracellular vesicles and tumor cells: sticky partners in metastasis. Trends in Cancer. 2022. doi:10.1016/j.trecan.2022.05.002

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  • Mittelheisser V, [...], Goetz JG, [...] Detappe A. Optimal Physicochemical Properties of Antibody–Nanoparticle Conjugates for Improved Tumor Targeting. Advanced Materials. 2022. doi:10.1002/adma.202110305

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  • Hyenne V, Goetz JG & Osmani N. Liquid Biopsies: Flowing Biomarkers. Microfluidics and Biosensors in Cancer Research pp 341–368. doi:10.1007/978-3-031-04039-9_14​

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  • André-Grégoire, G., [...], Hyenne V, Goetz JG, Bidère N, Gavard J. Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma. iScience. 25, 105118. 2022. doi:10.1016/j.isci.2022.105118

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  • Adam A, Harlepp C, [...], Goetz JG, [...], Mertz D. Core-shell iron oxide@stellate mesoporous silica for combined near-infrared photothermia and drug delivery: Influence of pH and surface chemistry. Colloids and Surfaces A. Volume 640. 2022. doi:10.1016/j.colsurfa.2022.128407

2021

  • Follain G, Osmani N, Gensbittel V, [...], Goetz JG. Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells. Sci Rep. 2021;11(1):13144. doi:10.1038/s41598-021-92515-2
     

  • Ghoroghi S, Mary B, Larnicol A, [...], Goetz JG, Hyenne V. Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes. Elife. 2021;10:1-29. doi:10.7554/eLife.61539

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  • Gensbittel V, Kräter M, Harlepp S, Busnelli I, Guck J, Goetz JG. Mechanical Adaptability of Tumor Cells in Metastasis. Developmental Cell. 2021. doi:10.1016/j.devcel.2020.10.011

 

  • Colin F, Gensbittel V, Goetz JG. Biomechanics: a driving force behind metastatic progression. Comptes Rendus Biol. 2021;344(3):249-262. doi:10.5802/crbiol.62
     

  • Ghoroghi S, Mary B, Asokan N, Goetz JG, Hyenne V. Tumor extracellular vesicles drive metastasis (it’s a long way from home). FASEB BioAdvances. 2021;3(11):930-943. doi:10.1096/fba.2021-00079
     

  • Osmani N, Follain G, Gensbittel V, Garcia-Leon MJ, Harlepp S, Goetz JG. Probing Intravascular Adhesion and Extravasation of Tumor Cells with Microfluidics. In: Methods in Molecular Biology. Vol 2294. Humana Press Inc.; 2021:111-132. doi:10.1007/978-1-0716-1350-4_8
     

  • Colin F, Schauer K, Hamiche A, [...], Schultz P, Goetz JG. The NANOTUMOR consortium – Towards the Tumor Cell Atlas. Biol Cell. 2021;113(6):boc.202000135. doi:10.1111/boc.202000135
     

  • Gaudin R, Goetz JG. Tracking Mechanisms of Viral Dissemination In Vivo. Trends Cell Biol. 2021;31(1):17-23. doi:10.1016/j.tcb.2020.09.005
     

  • Gensbittel V, Busnelli I, Osmani N, Goetz JG. Nanoluminal Signaling Shapes Collective Metastasis. Trends in Cancer. 2021;7(1):9-11. doi:10.1016/j.trecan.2020.11.003

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  • Mary B, Ghoroghi S, Goetz JG, Hyenne V. Les vésicules extracellulaires tumorales favorisent la formation de niches pré-métastatiques. Médecine/Sciences. 2021 ; 37 : 1116-8. doi:10.1051/medsci/2021203

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  • Verweij, F, [...], Goetz JG, Hyenne V, [...], Peinado H. The power of imaging to understand extracellular vesicle biology in vivo. Nature Methods. 2021. doi:10.1038/s41592-021-01206-3

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  • Murphy KJ, Reed DA, Vennin C, [...], Timpson P. Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status. Sci Adv. 2021;7(40):22. doi:10.1126/sciadv.abh0363
     

  • Gaudin R, Goetz JG. Tracking Mechanisms of Viral Dissemination In Vivo. Trends in Cell Biology. 2021. doi:10.1016/j.tcb.2020.09.005

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  • Liu F, Niko Y, Bouchaala R, [...] Klymchenko A. Drug‐Sponge Lipid Nanocarrier for in Situ Cargo Loading and Release Using Dynamic Covalent Chemistry. Angew Chemie Int Ed. 2021;60(12):6573-6580. doi:10.1002/anie.202014259
     

  • Belcastro E, Rehman AU, Remila L, [...] Schini-Kerth VB. Fluorescent nanocarriers targeting VCAM-1 for early detection of senescent endothelial cells. Nanomedicine Nanotechnology, Biol Med. 2021;34:102379. doi:10.1016/j.nano.2021.102379

2020

  • Follain G, Herrmann D, Harlepp S, [...], Timpson P, Goetz JG. Fluids and their mechanics in tumour transit: shaping metastasis. Nat Rev Cancer. 2020;20(2):107-124. doi:10.1038/s41568-019-0221-x
     

  • Mary B, Ghoroghi S, Hyenne V, Goetz JG. Live tracking of extracellular vesicles in larval zebrafish. In: Methods in Enzymology. Vol 645. Academic Press; 2020:243-275. doi:10.1016/bs.mie.2020.07.013

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  • Follain G, Gensbittel V, Mary B, [...], Goetz JG. Influence de la mécanique des fluides sur la formation des métastases. médecine/sciences. 2020;36(10):872-878. doi:10.1051/medsci/2020158
     

  • Krummel M, Hu K, de Vries EGE, Goetz JG, et al. Visualizing Cancer. Cancer Cell. 2020;38(6):753-756. doi:10.1016/j.ccell.2020.11.014
     

  • Perro M, Goetz JG, A Peixoto. Intra-vital microscopy. Imaging from Cells to Animals in Vivo, Book Chapter 2. ISBN 9781138041097
     

  • Mittelheisser V, Banerjee M, Pivot X, Charbonnière LJ, Goetz JG, Detappe A. Leveraging Immunotherapy with Nanomedicine. Adv Ther. 2020;3(12):2000134. doi:10.1002/adtp.202000134
     

  • Li B, Harlepp S, Gensbittel V, [...], Mertz D. Near infra-red light responsive carbon nanotubes@mesoporous silica for photothermia and drug delivery to cancer cells. Mater Today Chem. 2020;17. doi:10.1016/j.mtchem.2020.100308
     

  • Mertz D, Harlepp S, Goetz JG, [...], Hébraud A. Nanocomposite Polymer Scaffolds Responding under External Stimuli for Drug Delivery and Tissue Engineering Applications. Adv Ther. 2020;3(2):1900143. doi:10.1002/adtp.20190014

2019

  • Osmani N, Follain G, García León MJ, [...], Goetz JG. Metastatic Tumor Cells Exploit Their Adhesion Repertoire to Counteract Shear Forces during Intravascular Arrest. Cell Rep. 2019;28(10):2491-2500.e5. doi:10.1016/j.celrep.2019.07.102
     

  • Hyenne V, Ghoroghi S, Collot M, [...], Goetz JG. Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo. Dev Cell. 2019;48(4):554-572.e7. doi:10.1016/j.devcel.2019.01.014
     

  • Verweij FJ, Hyenne V, Van Niel G, Goetz JG. Extracellular Vesicles: Catching the Light in Zebrafish. Trends Cell Biol. 2019;29(10):770-776. doi:10.1016/j.tcb.2019.07.007
     

  • Osmani N, Goetz JG. Multiscale Imaging of Metastasis in Zebrafish. Trends in Cancer. 2019;5(12):766-778. doi:10.1016/j.trecan.2019.10.003
     

  • Verweij FJ, Revenu C, Arras G, [...] van Niel G. Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo. Dev Cell. 2019;48(4):573-589.e4. doi:10.1016/j.devcel.2019.01.004
     

  • San Juan BP, Garcia-Leon MJ, Rangel L, Goetz JG, Chaffer CL. The Complexities of Metastasis. Cancers (Basel). 2019;11(10):1575. doi:10.3390/cancers11101575
     

  • Hetmanski JHR, de Belly H, Busnelli I, [...] Caswell PT. Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration. Dev Cell. 2019;51(4):460-475.e10. doi:10.1016/j.devcel.2019.09.006
     

  • Ayala-Nunez NV, Follain G, Delalande F, [...] Goetz JG, Gaudin R. Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells. Nat Commun. 2019;10(1):4430. doi:10.1038/s41467-019-12408-x
     

  • Perton F, Harlepp S, Follain G, [...], Mertz D. Wrapped stellate silica nanocomposites as biocompatible luminescent nanoplatforms assessed in vivo. J Colloid Interface Sci. 2019;542:469-482. doi:10.1016/j.jcis.2019.01.098

2018

  • Follain G, Osmani N, Azevedo AS, [...], Goetz JG. Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells. Dev Cell. 2018;45(1):33-52.e12. doi:10.1016/j.devcel.2018.02.015
     

  • Hyenne V, Labouesse M, Goetz JG. The Small GTPase Ral orchestrates MVB biogenesis and exosome secretion. Small GTPases. 2018;9(6):445-451. doi:10.1080/21541248.2016.1251378
     

  • Goetz JG. Exploiting Anatomical Landmarks for Efficient In Vivo CLEM. Trends Biochem Sci. 2018;43(10):744-747. doi:10.1016/j.tibs.2018.08.003
     

  • Follain G, Osmani N, Fuchs C, Allio G, Harlepp S, Goetz JG. Using the Zebrafish Embryo to Dissect the Early Steps of the Metastasis Cascade. In: Methods in Molecular Biology. Vol 1749. Humana Press Inc.; 2018:195-211. doi:10.1007/978-1-4939-7701-7_15
     

  • Goetz JG. Metastases go with the flow. Science (80- ). 2018;362(6418):999-1000. doi:10.1126/science.aat9100
     

  • Chaffer CL, Goetz JG. CD44 Orchestrates Metastatic Teamwork. Dev Cell. 2018;47(6):691-693. doi:10.1016/j.devcel.2018.11.038
     

  • Follain G, Goetz JG. Synergistic Mechano-Chemical Sensing by Vascular Cilia. Trends Cell Biol. 2018;28(7):507-508. doi:10.1016/j.tcb.2018.04.005
     

  • Mammadova-Bach E, [...], Goetz JG, Orend G, Lefebvre O. Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma. Biol Cell. 2018;110(8):178-195. doi:10.1111/boc.201800007
     

  • Ezzoukhry Z, Henriet E, Cordelières FP, [...], Saltel F.. Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation. Nat Commun. 2018;9(1):2031. doi:10.1038/s41467-018-04461-9
     

  • Osmani N, Pontabry J, Comelles J, [...], Labouesse M. An Arf6- and caveolae-dependent pathway links hemidesmosome remodeling and mechanoresponse. Spang A, ed. Mol Biol Cell. 2018;29(4):435-451. doi:10.1091/mbc.E17-06-0356

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